Title
Topic
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Müftü and Özdemir receive Army Research Laboratory grant
“Sinan Müftü, College of Engineering distinguished professor of mechanical and industrial engineering, and Ozan Özdemir, assistant professor of mechanical and industrial engineering, are leading a team that was awarded a $4.38 million grant from the Army Research Laboratory to advance wire-arc direct energy deposition for large-format metal additive manufacturing.”
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‘Carvings in Stone: Design Research for Public Health Investigations in the Age of COVID-19’
“The COVID-19 pandemic presented complex challenges to public health research involving human subjects, necessitating creative thinking to maintain safe and productive qualitative data collection. In this paper, we describe how an interdisciplinary team overcame these challenges by translating in-person workshops into at-home design probes to explore connections between university students’ climate change attitudes and their health. … This case study provides insight into how pandemic-imposed restrictions presented a novel opportunity to reconceptualize how we collect qualitative data in public health research and summarizes the unique benefits of integrating such design-based approaches.” Find the paper and authors list at Design for…
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Zhang receives NSF grant to harness magnonic nonreciprocity
“Electrical and computer engineering assistant professor Xufeng Zhang, in collaboration with Boston University, was awarded a $420,000 NSF grant for ‘Harnessing Magnonic Nonreciprocity Through Dissipation Engineering.’ This project will investigate the principals of energy dissipation in magnonic systems and engineering approaches for manipulating dissipations.”
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‘An Empirical Study of How Service Designers Use Metrics’
“Scholars have advocated for the importance of evaluation in service design, proposing comprehensive frameworks for such integration in design processes. This research seeks to complement existing theoretical studies by providing empirical insights into the utilization of metrics by practicing service designers. Our study presents findings derived from a global survey and in-depth interviews conducted with service designers from eleven countries.” Find the paper and full list of authors at She Ji: The Journal of Design, Economics, and Innovation.
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Ghoreishi receives funding to study AI in harsh environments
“Fatemeh Ghoreishi, assistant professor of civil engineering, received a $60,000 grant from the U.S. Army for ‘BRITE: Bayesian Inference and Preference Learning for Unknown and Time-Sensitive Environments’ to further [her] research on AI systems in unpredictable environments.”
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Abur receives NSF grant to integrate renewable energy into power grids
“Electrical and computer engineering professor Ali Abur was awarded a $350,000 grant from the NSF for ‘Robust Transient State Estimation for Three-Phase Power Systems.’ The project aims to facilitate the efficient integration of inverter-based renewable energy sources into future generation of power systems.”
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‘Milk Exosomes Anchored With Hydrophilic and Zwitterionic Motifs Enhance Mucus Permeability for Applications in Oral Gene Delivery’
“Exosomes have emerged as a promising tool for the delivery of drugs and genetic materials, owing to their biocompatibility and non-immunogenic nature. However, challenges persist in achieving successful oral delivery due to their susceptibility to degradation in the harsh gastrointestinal (GI) environment and impeded transport across the mucus-epithelium barrier. To overcome these challenges, we have developed high-purity bovine milk exosomes (mExo) as a scalable and efficient oral drug delivery system, which can be customized by incorporating hydrophilic and zwitterionic motifs on their surface.” Find the paper and full list of authors at Biomaterials Science.
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‘Persistent Anisotropy of the Spin Cycloid in BiFeO3 Through Ferroelectric Switching’
“A key challenge in antiferromagnetic spintronics is the control of spin configuration on nanometer scales applicable to solid-state technologies. Bismuth ferrite (BiFeO3) is a multiferroic material that exhibits both ferroelectricity and canted antiferromagnetism at room temperature, making it a unique candidate in the development of electric-field controllable magnetic devices. … This study provides understanding of the antiferromagnetic texture in BiFeO3 and paves new avenues for designing magnetic textures and spintronic devices.” Find the paper and full list of authors at ArXiv.
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Dai receives patent for ‘Biodegradable Elastic Hydrogels for Bioprinting’
From the patent’s abstract: “Disclosed herein are hydrogel compositions comprising a triblock copolymer having a formula A-B-A, wherein A is a polycaprolactone (PCL) block or a polyvalerolactone (PVL) block and B is a polyethylene glycol (PEG) block. Also disclosed are methods of making a hydrogel comprising providing a photoinitiator and a triblock copolymer having a formula A-B-A, wherein the triblock copolymer comprises one or more ethylenically unsaturated moieties; and photocrosslinking the triblock copolymer, thereby forming a hydrogel.”
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Daramola elected Scialog fellow in sustainable minerals, metals and materials initiative
“Chemical engineering assistant professor Damilola Daramola has been named a Fellow of the Scialog initiative on Sustainable Minerals, Metals, and Materials. This interdisciplinary community of Fellows represents institutions across the United States and Canada and brings together expertise from fields including chemistry, materials science, geology, ecology, engineering, mining, computational science, physics and more. The community focuses on ensuring a sustainable future.”
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Needa Brown receives Women’s Health Innovation Grant
As part of Governor Maura Healey’s support of the Massachusetts Life Science Center’s Women’s Health Initiative, Needa Brown, assistant teaching professor of physics at Northeastern University, has received funding for her project “InCITE: A Biomaterial Platform to Overcome Barriers to Drug Delivery.”
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Whitford receives NIH grant to ‘enable translation’ across ribosomes
“This award will use theoretical models and high-performance computing to study the ribosome, a massive molecular assembly composed of hundreds of thousands of atoms. The ribosome is responsible for translating our genes into proteins, making its function central to all life. In this study, we will identify the molecular factors that control protein synthesis in bacteria and higher-level organisms. Insights into bacteria will aim to identify novel antibiotics, while the study of human ribosomes can shed light on a range of diseases, including metabolic diseases and forms of cancer.”
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Weng receives funding to identify small molecules involved in diseases like Alzheimer’s, Parkinson’s
“The proposed research aims to develop a plant-based drug screening platform to identify small molecules that can disrupt protein and RNA aggregation associated with neurodegenerative diseases such as Huntington’s, Alzheimer’s and Parkinson’s. The project will utilize the unique lyciumin peptide biosynthesis pathway in plants to generate a diverse library of cyclic peptides. These peptides will be screened in engineered tobacco BY-2 cells … to identify compounds that alleviate cellular toxicity and alter aggregation kinetics. … The established screening platform and identified compounds will be made available to the research community, potentially offering new tools and therapeutic strategies.”
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‘Genome-Wide Association Identifies a BAHD Acyltransferase Activity that Assembles an Ester of Glucuronosylglycerol and Phenylacetic Acid’
“Genome-wide association studies (GWAS) are an effective approach to identify new specialized metabolites and the genes involved in their biosynthesis and regulation. In this study, GWAS of Arabidopsis thaliana soluble leaf and stem metabolites identified alleles of an uncharacterized BAHD-family acyltransferase (AT5G57840) associated with natural variation in three structurally related metabolites. … Together, this work extends our understanding of the catalytic diversity of BAHD acyltransferases and uncovers a pathway that involves contributions from both phenylalanine and lipid metabolism.” Find the paper and full list of authors at the National Library of Medicine.
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‘The Evolutionary Origin of Naturally Occurring Intermolecular Diels-Alderases From Morus alba’
“Biosynthetic enzymes evolutionarily gain novel functions, thereby expanding the structural diversity of natural products to the benefit of host organisms. Diels-Alderases (DAs), functionally unique enzymes catalysing [4 + 2] cycloaddition reactions, have received considerable research interest. However, their evolutionary mechanisms remain obscure. Here, we investigate the evolutionary origins of the intermolecular DAs in the biosynthesis of Moraceae plant-derived Diels-Alder-type secondary metabolites. Our findings suggest that these DAs have evolved from an ancestor functioning as a flavin adenine dinucleotide-dependent oxidocyclase, which catalyses the oxidative cyclisation reactions of isoprenoid-substituted phenolic compounds.” Find the paper and authors list at the National Library of…
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‘Developing and Sustaining Northeastern’s Ed.D. Program During and Post Pandemic’
“Northeastern University’s Ed.D. faculty faced unique challenges during the pandemic and racial reckoning following George Floyd’s murder. During this period, however, we found opportunities to adapt and improve our program. We prioritized compassion and connection. We made significant strides in curriculum development through design and implementation of three new concentrations. We focused all program elements on how social justice works in a variety of educational settings. We altered our approach to data collection and doctoral supervision. In so doing, we were able to maintain consistency for our students and develop a closer bond with our faculty colleagues.”
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‘Design for Emergency: How Digital Technologies Enabled an Open Design Platform to Respond to COVID-19’
“In the COVID-19 pandemic, digital technologies (DT) supported the design and implementation of solutions addressing new needs and living conditions. We describe Design for Emergency, a digital open design platform developed to ideate solutions for people’s fast-changing needs in the pandemic, to analyze how DT can affect human-centered design processes during emergencies. We illustrate how DT: i) helped quickly collect and analyse people’s needs…; ii) facilitated the creation of a virtual network of stakeholders and an open-innovation digital platform; iii) inspired the ideation of solutions.” Find the paper and full list of authors at Interacting With Computers.
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‘Monodromy of the Casimir Connection of a Symmetrisable Kac–Moody Algebra’
“Let g be a symmetrisable Kac–Moody algebra and V an integrable g–module in category O. We show that the monodromy of the (normally ordered) rational Casimir connection on V can be made equivariant with respect to the Weyl group W of g, and therefore defines an action of the braid group Bw on V. … This action is canonically equivalent to the quantum Weyl group action of Bw on a quantum deformation of V, that is an integrable, category O module V over the quantum group Uhg such that V/hV is isomorphic to V.” Find authors at Inventiones Mathematicae.
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Engineering professor wants to revolutionize wireless communication by manipulating ‘acoustic waves in solids’
Assistant professor of electrical and computer engineering Siddhartha Ghosh has received two prestigious early career awards for his work on radio frequency front-end devices, developing materials that convert radio signals into acoustic waves at the microchip level.