This article examines cellular unjamming, “the collective fluidization of cell motion… linked to many biological processes, including development, wound repair, and tumor growth.” Because of the complex, linked effects between various cellular mechanisms, “the role of compressive stress in unjamming transitions during cancer progression remains unknown. Here, [the authors] investigate which mechanism dominates in a [single] dense, mechanically stressed” layer. Their findings add nuance to models of “collective cell motion in tumor development and breast cancer progression.”

Find the paper and the full list of authors at Frontiers in Cell and Developmental Biology.