Title

Topic

  • ‘The Clinical Trials Puzzle: How Network Effects Limit Drug Discovery’

    “The depth of knowledge offered by post-genomic medicine has carried the promise of new drugs, and cures for multiple diseases. To explore the degree to which this capability has materialized, we extract meta-data from 356,403 clinical trials spanning four decades, aiming to offer mechanistic insights into the innovation practices in drug discovery. We find … the tested drugs target only 12% of the human interactome. If current patterns persist, it would take 170 years to target all druggable proteins.” Read the paper and see the full list of authors in ArXiv.

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  • ‘HoLA Robots: Mitigating Plan-Deviation Attacks in Multi-Robot Systems’

    “Emerging multi-robot systems rely on cooperation between humans and robots, with robots following automatically generated motion plans to service application-level tasks. Given the safety requirements associated with operating in proximity to humans and expensive infrastructure, it is important to understand and mitigate the security vulnerabilities of such systems. … We focus on centralized systems, where a *central entity* (CE) is responsible for determining and transmitting the motion plans to the robots, which report their location as they move following the plan.” Read the paper and see the full list of authors in ArXiv.

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  • Ocean Genome Legacy Center partners with 1% for the Planet

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    A researcher works at the Ocean Genome Legacy Center.

    Northeastern’s Ocean Genome Legacy Center has become an Environmental Partner with 1% for the Planet, which brings together companies and individuals to support environmental nonprofits.

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  • Ivanova speaks at Nardone Family Seminar on plastic pollution

    “In this installment of the Nardone Family Seminar series, Maria Ivanova, director of the School of Public Policy and Urban Affairs and professor of public policy at Northeastern University, [discussed] the role of two small states—Rwanda and Peru—that successfully advocated for a resolution to end plastic pollution by 2040.”

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  • Paper from the Ocean Genome Legacy Center, ‘Greater Than pH 8: The pH Dependence of EDTA as a Preservative of High Molecular Weight DNA’

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    “Ethylenediaminetetraacetic acid (EDTA) is a divalent cation chelator and chemical preservative that has been shown to be the active ingredient of the popular DNA preservative DESS. EDTA may act to reduce DNA degradation during tissue storage by sequestering divalent cations that are required by nucleases naturally occurring in animal tissues. … Increasing the pH of EDTA-containing preservative solutions may improve their effectiveness as DNA preservatives.” Read “Greater Than pH 8: The pH Dependence of EDTA as a Preservative of High Molecular Weight DNA in Biological Samples” and find the full list of authors in PLOS ONE.

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  • ‘Single-Pass Streaming Algorithms for Correlation Clustering’

    “We study correlation clustering in the streaming setting. This problem has been studied extensively and numerous algorithms have been developed, most requiring multiple passes over the stream. … We present a single-pass algorithm that obtains a 5-approximation using O(n) space. The algorithm itself is extremely simple and has implications beyond the streaming setting (such as for dynamic and local computation algorithms). The approximation analysis, on the other hand, is delicate and in fact tight.” Read the paper and see the full list of authors in the Society for Industrial and Applied Mathematics.

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  • ‘Dynamic Algorithms for Maximum Matching Size’

    “We study fully dynamic algorithms for maximum matching. This is a well-studied problem, known to admit several update-time/approximation trade-offs. For instance, it is known how to maintain a 1/2-approximate matching in (poly log n) update time or a 2/3-approximate match­ing in O(√n) update time, where n is the number of vertices. … We show that when the goal is to maintain just the size of the matching (and not its edge-set), then these bounds can indeed be improved.” Read the paper and see the full list of authors in the Society for Industrial and Applied Mathematics.

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  • ‘Decadal Application of WRF/Chem Under Future Climate and Emission Scenarios’

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    “This work presents new climate and emissions scenarios to investigate changes on future meteorology and air quality in the U.S. Here, we employ a dynamically downscaled Weather Research and Forecasting model coupled with chemistry (WRF/Chem) simulations that use two Intergovernmental Panel on Climate Change scenarios (i.e., A1B and B2) integrated with explicitly projected emissions from a novel Technology Driver Model (TDM).” Read “Decadal Application of WRF/Chem Under Future Climate and Emission Scenarios: Impacts of Technology-Driven Climate and Emission Changes on Regional Meteorology and Air Quality” and see the full list of authors in Atmosphere.

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  • SMART Center receives $4 million DARPA grant for thermal imaging program

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    The SMART Center at Northeastern University, whose mission statement “aims to conceive and pilot disruptive technological innovation in smart devices and systems,” has received a $4 million grant from the Defense Advanced Research Projects Agency (DARPA), under their Optomechanical Thermal Imaging program. The SMART Center proposed the development of “Nano-opto-mechanical Piezoelectric Resonant Infrared-sensitive Metamaterials for Quantum-Limited Photodetection,” which would work to develop an exceptionally small detector of infrared light.

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  • Lehman elected President of IEEE Power Electronics Society

    Professor of electrical and computer engineering Bradley Lehman has been elected president of the IEEE Power Electronics Society. The Power Electronics Society studies “technology [that] encompasses the effective use of electronic components, the application of circuit theory and design techniques, and the development of analytical tools for efficient conversion, control, and condition of electric power,” they write on their website.

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  • ‘Who Wants To Cooperate—And Why? Attitude and Perception of Crowd Workers in Online Labor Markets’

    “Existing literature and studies predominantly focus on how crowdsource workers individually complete tasks and projects. Our study examines crowdsource workers’ willingness to work collaboratively. We report results from a survey of 122 workers on a leading online labor platform (Upwork) to examine crowd workers’ behavioral preferences for collaboration. … We then test if actual cooperative behavior matches with workers’ behavioral preferences through an incentivized social dilemma experiment. We find that respondents cooperate at a higher rate (85%) than reported in previous comparable studies (between 50-75%).” Read the paper and see the full list of authors in ArXiv.

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  • ‘Interphase Chromosomes of the Aedes Aegypti Mosquito Are Liquid Crystalline and Can Sense Mechanical Cues’

    In “Interphase chromosomes of the Aedes aegypti mosquito are liquid crystalline and can sense mechanical cues,” the authors observe “the three-dimensional architecture of the Aedes aegypti genome,” a species of mosquito. Their observations “[provide] a possible physical mechanism linking mechanical cues to gene regulation.” Find the paper and the full list of authors at Nature Communications.

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  • Building a better hologram: Just add noise

    Researchers from Northeastern University, in collaboration with Nanjing University, have broken a “theoretical limit” in metasurface capacities—a.k.a. “holograms.” By introducing carefully engineered noise into Jones matrices, they have produced “the highest capacity reported for polarization multiplexing.” They demonstrate this raised capacity across “11 independent holographic images.” Read “Breaking the Limitation of Polarization Multiplexing in Optical Metasurfaces with Engineered Noise” and find the full list of authors at Science.

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  • Fu named ACM Fellow for contributions to computer security

    “Professor Kevin Fu was named a Fellow of the Association for Computing Machinery for contributions to computer security, and especially to the secure engineering of medical devices.”

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  • ‘Lineage-Mismatched Mitochondrial Replacement … Effectively Restores the Original Proteomic Landscape of Recipient Cells’

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    “Here an inducible mitochondrial depletion modelis used to study how cells lacking endogenous mitochondria respond, on a global protein expression level, to transplantation with lineage-mismatched (LM) mitochondria. It is shown that LM mitochondrial transplantation does not alter the proteomic profile in nonmitochondria–depleted recipient cells; however, enforced depletion of endogenous mitochondria results in dramatic changes in the proteomic landscape, which returns to the predepletion state following internalization of LM mitochondria.” Find “Lineage-Mismatched Mitochondrial Replacement in an Inducible Mitochondrial Depletion Model Effectively Restores the Original Proteomic Landscape of Recipient Cells” and the full list of authors in Advanced Biology.

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  • International Business Today: Podcast from the D’Amore-McKim School of Business

    “The D’Amore-McKim School of Business’ international business and strategy academic group is launching the International Business Today podcast. Episodes will explore the most critical business issues through the lens of cutting-edge research. This podcast is for all global business professionals and any student who hopes to work for a multinational organization in the future.”

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  • The straightest line between two points: When your map’s incomplete

    The authors of “Finding shortest and nearly shortest path nodes in large substantially incomplete networks by hyperbolic mapping” have determined that large, real-world networks “are not random but are organized according to latent-geometric rules.” This being the case, they argue that, when “mapped to points in latent hyperbolic spaces,” they can calculate shortest paths “along geodesic curves connecting endpoint nodes.” In other words, they can get from A to C, without knowing B’s location. Read “Finding shortest and nearly shortest path nodes in large substantially incomplete networks by hyperbolic mapping” and see the full list of authors in Nature Communications.

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  • Zhang-Wu wins Research Impact Award for multilingual research

    “Qianqian Zhang-Wu, assistant professor of English and director of multilingual writing, has won the 2023 CCCC Research Impact Award for ‘Languaging Myths and Realities: Journeys of Chinese International Students.’ The Conference on College Composition and Communication (CCCC) is a constituent organization within the National Council of Teachers of English.”

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  • Spring 2023 Spark Fund awardees announced for Northeastern innovators

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    Professors Ryan Koppes, Yaning Li, Diomedes Logothetis, Carolyn Lee-Parsons, Edmund Yeh and Ke Zhang have all received Spark Funds from the Center for Research Innovation for Spring 2023. “The Spark Fund supports commercially valuable inventions (from any field) from university researchers in earlier stages of development. The goal of the award is to advance a technology or suite of technologies from academia towards commercialization.”

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  • Li receives NSF CAREER Grant for pathogen work

    “Assistant professor Jiahe Li was awarded a $636,000 National Science Foundation CAREER award for a project titled ‘Understanding and Harnessing Host-derived Small RNAs Against Opportunistic Pathogens.’”

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  • How the ‘two ingredients of language’ come from different regions of the brain

    The authors of “Phonetic Categorization Relies on Motor Simulation, But Combinatorial Phonological Computations Are Abstract” note two elements required in human language, categorization (identifying words as “distinct units”) and combination (distinguishing between units). The authors explore these mechanisms “using transcranial magnetic stimulation. [They] show that speech categorization engages the motor system. … In contrast, the combinatorial computation of syllable structure engages Broca’s area,” a region within the brain’s frontal lobe. They “conclude that the two ingredients of language—categorization and combination—are distinct functions in human brains.” Read their paper and see the full list of authors in Scientific Reports.

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  • Patent for a ‘Zero Power Plasmonic Microelectromechanical Device’

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    “Professor Matteo Rinaldi and research assistant professor Zhenyun Qian were awarded a patent for designing a ‘Zero Power Plasmonic Microelectromechanical Device.’ According to the abstract, the ‘device is capable of specifically sensing electromagnetic radiation and performing signal processing operations. … The devices can continuously monitor an environment and wake up an electronic circuit upon detection of a specific trigger signature of electromagnetic radiation.'”

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  • ‘Byzantine Resilience at Swarm Scale: A Decentralized Blocklist Protocol From Inter-Robot Accusations’

    “The Weighted-Mean Subsequence Reduced (W-MSR) algorithm, the state-of-the-art method for Byzantine-resilient design of decentralized multi-robot systems, is based on discarding outliers received over Linear Consensus Protocol (LCP). Although W-MSR provides well-understood theoretical guarantees relating robust network connectivity to the convergence of the underlying consensus, the method comes with several limitations preventing its use at scale. … In this work, we propose a Decentralized Blocklist Protocol (DBP) based on inter-robot accusations.” Read the paper and see the full list of authors in ArXiv.

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  • ‘Beating (1 – 1/e)-Approximation for Weighted Stochastic Matching’

    “In the stochastic weighted matching problem, the goal is to find a large-weight matching of a graph when we are uncertain about the existence of its edges. In particular, each edge e has a known weight we but is realized independently with some probability pe. The algorithm may query an edge to see whether it is realized. We consider the well-studied query commit version of the problem, in which any queried edge that happens to be realized must be included in the solution.” Find the paper and the full list of authors at SIAM.

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  • ‘Beating Greedy Matching in Sublinear Time’

    “We study sublinear time algorithms for estimating the size of maximum matching in graphs. Our main result is a (½ + Ω(1))-approximation algorithm which can be implemented in O(n1+ε) time, where n is the number of vertices and the constant ε > 0 can be made arbitrarily small. The best known lower bound for the problem is Ω(n), which holds for any constant approximation.” Read the paper and see the full list of authors at the Society for Industrial and Applied Mathematics.

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  • ‘Single-Pass Streaming Algorithms for Correlation Clustering’

    “We study correlation clustering in the streaming setting. This problem has been studied extensively and numerous algorithms have been developed, most requiring multiple passes over the stream. For the important case of single-pass algorithms, recent work of Assadi and Wang [8] obtains a c-approximation using Õ(n) space where c > 105 is a constant and n is the number of vertices to be clustered. We present a single-pass algorithm that obtains a 5-approximation using O(n) space.” Read the paper and see the full list of authors at the Society for Industrial and Applied Mathematics.

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  • ‘Dynamic Algorithms for Maximum Matching Size’

    “We study fully dynamic algorithms for maximum matching. This is a well-studied problem, known to admit several update-time/approximation trade-offs. … It has been a long-standing open problem to determine whether either of these bounds can be improved. In this paper, we show that when the goal is to maintain just the size of the matching (and not its edge-set), then these bounds can indeed be improved.”

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  • ‘Sublinear Algorithms for TSP via Path Covers’

    “We study sublinear time algorithms for the traveling salesman problem (TSP). First, we focus on the closely related maximum path cover problem, which asks for a collection of vertex disjoint paths that include the maximum number of edges. Our analysis of the running time uses connections to parallel algorithms and is information-theoretically optimal up to poly log n factors. Additionally, we show that our approximation guarantees for path cover and (1,2)-TSP hit a natural barrier: We show better approximations require better sublinear time algorithms for the well-studied maximum matching problem.” Find the paper and full list of authors at ArXiv.

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  • Using computer science to tell stories ‘that make a difference’

    In “Code for What?: Computer Science for Storytelling and Social Justice,” Clifford Lee and co-author Elisabeth Soep ask, “What if coding were a justice-driven medium for storytelling rather than a narrow technical skill?” The authors show why computer coding can be more than a career-motivated pursuit, but can also be used for the social good. “Code for What?” tells the “stories of a diverse group of young people in Oakland, California, who combine journalism, data, design, and code to create media that makes a difference.”

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  • Chowdhury awarded patent for intelligent wi-fi access points

    Professor Kaushik Chowdhury received a patent for work on the “Method and apparatus for access point discovery in dense WiFi networks.” The abstract to the patent offers “Systems, devices, and methods for access point discovery in a wireless network,” which rely on phase shift methods “encoded into bits in selected ones of a plurality of subcarriers.”

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