Alexandros Makriyannis George D. Behrakis Chair in pharmaceutical biotechnology, director of the Center for Drug Discovery, professor of chemistry and chemical biology a.makriyannis@neu.edu 617.373.4200 Expertise drug design synthesis, endocannabinoid system in drug discovery, interactions of drugs with membranes Alexandros Makriyannis in the Press Scientists map the receptor that makes weed work “People have been using cannabis for a variety of therapeutic indications for centuries,” says Alexandros Makriyannis, director of Northeastern University’s Center for Drug Discovery, and a co-author of this new research, published in Nature. In the 1960s, scientists finally started to figure that out as well. And by the 1980s, Eli Lilly had developed a […] How Weed Works Its Magic Just Got Easier To Understand “We found that the CB1 receptor consists of multiple sub-pockets and channels,” Dr. Alexandros Makriyannis, director of Northeastern University’s Center for Drug Discovery and a member of the international team of researchers who mapped CB1, said in a press statement. “This complex structure will allow chemists to design diverse compounds that specifically target portions of […] Alexandros Makriyannis for Northeastern Global News Cannabis will transform medicine—once we figure out how to get rid of its side effects Cannabis will transform medicine—once we figure out how to get rid of its side effects To produce better drugs for chronic pain, mental illness, and other health problems, professor Alexandros Makriyannis is making new molecules. Structure of the brain’s ‘marijuana receptor’ revealed Structure of the brain’s ‘marijuana receptor’ revealed New research by a team, including Northeastern’s Alexandros Makriyannis, reveals how THC gets into brain cells. Drug discovery and delivery research at Northeastern’s pharmacy school spurs innovation, collaboration Drug discovery and delivery research at Northeastern’s pharmacy school spurs innovation, collaboration Throughout Northeastern’s School of Pharmacy, researchers are making progress in solving a range of pressing health challenges. An off-switch for drugs’ toxic side effects An off-switch for drugs’ toxic side effects New research from the Center for Drug Discovery at Northeastern presents a series of molecules that can be controllably deactivated, thereby reducing the side effects of potentially valuable drugs. An interdisciplinary approach to drug-abuse research An interdisciplinary approach to drug-abuse research The Center for Drug Discovery at Northeastern hosted the 10th annual symposium on current trends in drug-abuse research earlier this month. Professor honored for his contributions to medicinal chemistry Professor honored for his contributions to medicinal chemistry Alexandros Makriyannis, the founding director of Northeastern’s Center for Drug Discovery, has received the annual Award in Medicinal Chemistry from the American Chemical Society. Northeastern explores biotech collaboration with Algeria Northeastern explores biotech collaboration with Algeria A delegation of Algerian government officials met last week with President Joseph E. Aoun and faculty members in the Bouvé College of Health Sciences with the hope of forging partnerships in the biotechnology sector. New weight-loss compound shows promise New weight-loss compound shows promise Northeastern's Center for Drug Discovery collaborates with National Institutes of Health on a therapeutic drug that could aid weight loss without side effects Pharmaceutical Biotech Scientist Discovers New Molecule to Treat Chronic Pain Pharmaceutical Biotech Scientist Discovers New Molecule to Treat Chronic Pain Northeastern University Pharmaceutical Sciences professor and Center for Drug Discovery director Alexandros Makriyannis and a team of researchers have created a synthetic molecule that could be used to treat chronic pain in patients with diseases such as diabetes or shingles. The findings were published in a recent issue of Psychopharmacology in an article titled “Discriminative […]
Scientists map the receptor that makes weed work “People have been using cannabis for a variety of therapeutic indications for centuries,” says Alexandros Makriyannis, director of Northeastern University’s Center for Drug Discovery, and a co-author of this new research, published in Nature. In the 1960s, scientists finally started to figure that out as well. And by the 1980s, Eli Lilly had developed a […]
How Weed Works Its Magic Just Got Easier To Understand “We found that the CB1 receptor consists of multiple sub-pockets and channels,” Dr. Alexandros Makriyannis, director of Northeastern University’s Center for Drug Discovery and a member of the international team of researchers who mapped CB1, said in a press statement. “This complex structure will allow chemists to design diverse compounds that specifically target portions of […]