Advances in proteome research have led to the ability to analyze “proteins from single cells by tandem mass spectrometry.” These advances “the potential to accurately quantify thousands of proteins across thousands of single cells,” but nevertheless face several issues in the areas of “accuracy and reproducibility.”
The authors of this study “propose best practices, quality controls and data-reporting recommendations to assist in the broad adoption of reliable quantitative workflows for single-cell proteomics.”
Read “Initial Recommendations for Performing, Benchmarking and Reporting Single-Cell Proteomics Experiments” and see the full list of authors in Nature Methods.