James Monaghan Associate Professor of Developmental Biology Expertise regenerative biology James Monaghan in the Press Article Discover What the Axolotl’s Limb-Regenerating Capabilities Have to Teach Us Somewhere in their genomes, “all animals have the ability,” says James Monaghan, a regeneration biologist at Northeastern University in Boston. After all, he points out, all animals grow body parts as embryos. Article Smithsonian Magazine Some Salamanders Can Regrow Lost Body Parts. Could Humans One Day Do the Same? Somewhere in their genomes, “all animals have the ability,” says James Monaghan, a regeneration biologist at Northeastern University in Boston. Article New York Post https://nypost.com/2019/10/28/salamander-that-eats-its-siblings-may-unlock-secrets-for-limb-regeneration/ It is an act that Northeastern University associate professor of biology James Monaghan believes could help with the ability to grow back human limbs, akin to the Marvel superhero Deadpool. Article Fox News Cannibalistic smiling salamander may unlock secrets for limb regeneration Known as an axolotl, this unique amphibian, which is described as “smiley-faced” and “feathery-gilled,” lives in Mexico and has been known to eat the limbs of its siblings for food. It is an act that Northeastern University associate professor of biology James Monaghan believes could help with the ability to grow back human limbs, akin to […] Article Axios Science sequence the genome of a regenerating salamander The critically endangered Mexican axolotl can regenerate body parts better than practically any other vertebrate on the planet. If a limb is lost, a limb can be regrown. “We need to figure out why and hopefully mimic that in humans,” says Northeastern University’s James Monaghan, who studies the biology of regeneration in the salamander species. Article New Scientist Forget the dentist’s drill, use lasers to heal teeth Open wide, this won’t hurt a bit. That might actually be true if the dentist’s drill is replaced by a promising low-powered laser that can prompt stem cells to make damaged hard tissue in teeth grow back. Such minimally invasive treatment could one day offer an easy way to repair or regrow our pearly whites. […] Article National Geographic Pictures: 5 Animals That Regrow Body Parts James Monaghan, a biologist at Boston’s Northeastern University, began studying axolotls during a grad school project and stuck with them since. “If they’re paralyzed in the back they can recover the functions of their legs … They can make all new neurons and new connections that allow them to use their legs again, which is […] Article The Scientist Nailing Regeneration “The work really highlights that mammals don’t completely lack the ability to regenerate—it’s just that the correct developmental signaling is not turned on,” said James Monaghan, a regeneration biologist at Northeastern University who was not involved with the study. “It shows for first time how similar mammalian digit regeneration is to amphibian limb regeneration.” Article Nature.com How nails regenerate lost fingertips ‘Really striking’ “It’s a fantastic paper,” says James Monaghan, a regeneration biologist at Northeastern University in Boston, Massachusetts. “It’s really striking that the cellular mechanisms and signalling pathways, like Wnt and FGF, all seem to be the same as those in salamanders.” It seems likely that these mechanisms will also apply to humans and other […] James Monaghan for Northeastern Global News This salamander can regenerate limbs like Deadpool. Can it teach us to do the same? This salamander can regenerate limbs like Deadpool. Can it teach us to do the same? Scientists are studying how the axolotl can regrow injured or lost body parts flawlessly, and without scarring, to see if humans could develop the same regenerative ability. Here’s what makes a great teacher Here’s what makes a great teacher The passion that drives James Monaghan is tissue regeneration; for Denise Garcia, it’s international diplomacy. While their disciplines couldn’t be more different, what earned them the 2018 University Excellence in Teaching Award is what they have in common—a passion for students on both the academic and human level. The salamander king The salamander king James Monaghan, an assistant professor of biology, studies the axolotl salamander, which can grow new limbs and parts of its spinal cord.