One big way that former Massachusetts Governor Michael Dukakis came to statewide fame – and ultimately the 1988 Democratic nomination for president – was as a late 1960s crusader against the excesses of the billboard industry in the Bay State.

Now 79 and teaching at Northeastern University and in California, Dukakis has come back to his roots – leading the opposition to pharmaceutical giant Sanofi U.S.’s plans for a big logo sign on the top of its 640 Memorial Drive building in Cambridge, overlooking the recently rehabbed Boston University Bridge at the gateway to the Charles River Basin.