MedScape Long-acting opioids related to unintentional overdose risk Long-acting opioids were associated with a greater than 2-fold risk for unintentional overdose compared with short-acting formulations, according to a cohort study published onlineFebruary 16 in JAMA Internal Medicine. Moreover, the risk was more than 5-fold greater in the first 2 weeks of using a long-acting opioid. “If replicated in other cohorts, our findings suggest […]