In soil-dwelling bacteria, scientists find a new weapon to fight drug-resistant superbugs
Los Angeles Times - 02/13/2018
“They’ve used a clever approach to mine for antibiotics,” said microbiologist Kim Lewis, who directs Northeastern University’s Antimicrobial Discovery Center and wasn’t involved in the work. By narrowing their search for the DNA signature of calcium dependence, they were able to find a needle in a haystack — and find a promising compound.
“Now we need to say, ‘You guys can do even better,'” Lewis said.
To demonstrate that their discovery is more than a one-time event, he said, Brady and his team need to identify and screen for additional DNA signatures that may predict potent antibiotic effects, “and go after them as well.”