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The perks of being a team of one

“While having people with diverse skills and experience on a founding team has significant benefits, their ability to work together effectively is just as important,” explains Kimberly A. Eddleston, the Schulze Distinguished Professor of Entrepreneurship and Montoni Research Fellow at the D’Amore-McKim School of Business at Northeastern University. “They need to be compatible, trustworthy, and able to communicate.”
PNAS

Disorder guides protein function

Cellular function requires biomolecules to undergo dynamic transitions that include folding, conformational rearrangements, and large-scale assembly. The result is a highly interdependent network of processes that is maintained by a balance of thermodynamic and kinetic factors. In molecular machines, each constituent biopolymer (i.e., a chain of residues) first folds to a low energy configuration/ensemble. These ordered polymers can then assemble into sophisticated architectures, […]